(2021) Diabetes and COVID-19; a review of possible mechanisms. Current pharmaceutical design. ISSN 1873-4286 (Electronic) 1381-6128 (Linking)
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Abstract
Coronavirus disease 2019 (SARS-CoV-2) (COVID-19) has recently raised worldwide public health concerns. The available data on COVID-19 in patients with diabetes is limited but generally indicate that there is an increased risk of developing COVID-19 infection in diabetic patients, which ultimately impact the overall patient's survival. Various aspects might be involved however, the exact mechanisms and interrelationships between diabetes and the novel COVID-19 have not yet been fully elucidated. This review summarizes the possible mechanisms by which present diabetes predispose individuals to COVID-19 infection, modulates the host-viral interactions and increases the risk of mortality. We hope this review can provide beneficial information for further studies and contribute for improved disease management of diabetic patients with COVID-19.
Item Type: | Article |
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Keywords: | COVID-19; Diabetes; Prognosis; Review; SARS-CoV-2; mechanism; risk factor. |
Journal or Publication Title: | Current pharmaceutical design |
Identification Number: | 10.2174/1381612827666210303141846 |
ISSN: | 1873-4286 (Electronic) 1381-6128 (Linking) |
Depositing User: | دکتر محبوبه عبداللهی |
URI: | http://eprints.thums.ac.ir/id/eprint/3318 |
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