Repository of Research and Investigative Information

Repository of Research and Investigative Information

Torbat Heydariyeh University of Medical Sciences

Metal-based nanoparticles for bone tissue engineering

(2020) Metal-based nanoparticles for bone tissue engineering. Journal of Tissue Engineering and Regenerative Medicine. ISSN 19326254

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Tissue is vital to the organization of multicellular organisms, because it creates the different organs and provides the main scaffold for body shape. The quest for effective methods to allow tissue regeneration and create scaffolds for new tissue growth has intensified in recent years. Tissue engineering has recently used some promising alternatives to existing conventional scaffold materials, many of which have been derived from nanotechnology. One important example of these is metal nanoparticles. The purpose of this review is to cover novel tissue engineering methods, paying special attention to those based on the use of metal-based nanoparticles. The unique physiochemical properties of metal nanoparticles, such as antibacterial effects, shape memory phenomenon, low cytotoxicity, stimulation of the proliferation process, good mechanical and tensile strength, acceptable biocompatibility, significant osteogenic potential, and ability to regulate cell growth pathways, suggest that they can perform as novel types of scaffolds for bone tissue engineering. The basic principles of various nanoparticle-based composites and scaffolds are discussed in this review. The merits and demerits of these particles are critically discussed, and their importance in bone tissue engineering is highlighted. © 2020 John Wiley & Sons, Ltd.

Item Type: Article
Keywords: bone growth; magnetic nanoparticles; metal nanoparticles; scaffold; tissue engineering
Journal or Publication Title: Journal of Tissue Engineering and Regenerative Medicine
Journal Index: ISI, Scopus
Publisher: John Wiley and Sons Ltd
Identification Number: 10.1002/term.3131
ISSN: 19326254
Depositing User: دکتر محبوبه عبداللهی

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