Repository of Research and Investigative Information

Repository of Research and Investigative Information

Torbat Heydariyeh University of Medical Sciences

Family history of diabetes and the risk of gestational diabetes mellitus in Iran: A systematic review and meta-analysis

(2017) Family history of diabetes and the risk of gestational diabetes mellitus in Iran: A systematic review and meta-analysis. Diabetes and Metabolic Syndrome: Clinical Research and Reviews. S99-S104. ISSN 18714021

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Abstract

Objective Gestational diabetes is the most prevalent metabolic disorder being firstly diagnosed during pregnancy. The relationship between the family history of diabetes and the gestational diabetes mellitus (GDM) has been investigated in several primary studies with a number of contradictions in the results. Hence, the purpose of the present study is to determine the relationship between the GDM and the family history of diabetes using the meta-analysis method. Method All published papers in main national and international databases were systematically searched with some specific keywords to find the related studies between 2000 and 2016. We calculated the odds ratio (OR) with 95 confidence interval (CI) in analysis for each study using a random-effect and Mantel-Haenzel method. We also determined heterogeneity among these 33 articles and their publication bias. Results We entered 33 relevant studies of 2516 articles into the meta-analysis process including 2697 women with family history of diabetes mellitus as well as 29134 women without. Of them, 954 and 4372 subjects developed GDM respectively. Combining the results of the primary studies using the meta-analysis method, the overall odds ratio of family history for developing GDM was estimated as of 3.46 (95 CI: 2.80�4.27). Conclusion This meta-analysis study revealed that the family history of diabetes is an important risk factor for the gestational diabetes mellitus. © 2016 Diabetes India

Item Type: Article
Keywords: Diabetes; Gestational diabetes mellitus; Family history of diabetes; Meta-analysis
Page Range: S99-S104
Journal or Publication Title: Diabetes and Metabolic Syndrome: Clinical Research and Reviews
Journal Index: ISI, Pubmed, Scopus
Volume: 11
Publisher: Elsevier Ltd
Identification Number: 10.1016/j.dsx.2016.12.016
ISSN: 18714021
Depositing User: دکتر محبوبه عبداللهی
URI: http://eprints.thums.ac.ir/id/eprint/245

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